Lupe is a Lieutenant in BESPA and is a subordinate to Arbeo Pippenden. She initially appears on Earth, pursuing the League Militaire forces to the Arti Gibralter space port in which she is involved in multiple battles. She later appears in space, assigned to the Motorad forces and is a part of numerous battles with the League Militaire.
When Uso Ewin was kidnapped, Lupe had him stripped and put in a bubble bath which she joined as well. In the bath she interrogated him by dunking his head in the water attempting to drown him, to determine if he was a Newtype or not and if he would join the Zanscare cause. Uso grabbed her bare breasts and ended up wrestling each other in the bath. Uso got away and Lupe had to chase him out of the mansion naked, while a guard dressed her. Soon enough, Uso was hanging onto the side of the mansion wall, with nothing but a towel wrapped around his neck. But soon enough, his dog Flanders and Haro were able to help him escape.
Lupe eventually dies after a final battle with Uso in space. She plows her damaged Bruckneg mobile suit into Pippenden's Birknau mobile armor, killing them both.